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Antimicrobial resistance in Neisseria gonorrhoeae: history, molecular mechanisms and epidemiological aspects of an emerging global threat BJM
Costa-Lourenço,Ana Paula Ramalho da; Santos,Késia Thaís Barros dos; Moreira,Beatriz Meurer; Fracalanzza,Sergio Eduardo Longo; Bonelli,Raquel Regina.
ABSTRACT Neisseria gonorrhoeae is the agent of gonorrhea, a sexually transmitted infection with an estimate from The World Health Organization of 78 million new cases in people aged 15-49 worldwide during 2012. If left untreated, complications may include pelvic inflammatory disease and infertility. Antimicrobial treatment is usually effective; however, resistance has emerged successively through various molecular mechanisms for all the regularly used therapeutic agents throughout decades. Detection of antimicrobial susceptibility is currently the most critical aspect for N. gonorrhoeae surveillance, however poorly structured health systems pose difficulties. In this review, we compiled data from worldwide reports regarding epidemiology and antimicrobial...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neisseria gonorrhoeae; Surveillance; Resistance mechanisms.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000400617
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Phenotypical characteristics of group B streptococcus in parturients BJID
Simoes,Jose Antonio; Alves,Valeria Moraes Neder; Fracalanzza,Sergio Eduardo Longo; Camargo,Rodrigo Pauperio Soares de; Mathias,Lenir; Milanez,Helaine Maria Besteti Pires; Brolazo,Eliane Melo.
Colonization by Group B Streptococcus (GBS) is highly prevalent among pregnant women, with prevalence rates ranging between 4% and 30%. The infection may be transmitted vertically and may result in serious neonatal consequences. In the period from November 2003 to May 2004, a cross-sectional study was carried out among 316 parturients at the Jundiaí Teaching Hospital to establish the prevalence of genital GBS colonization, to identify the factors associated with colonization and the characteristic phenotypes of these streptococci. Samples from rectal and vaginal areas were collected for selective culture in Todd-Hewitt broth. Susceptibility to 7 antimicrobial agents was tested using the antibiotic diffusion disk technique, and the isolated strains were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus agalactiae; Neonatal infections; Antimicrobial resistance; Serum type; GBS; Pregnant woman.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200019
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